Tenofovir Alafenamide Hemifumarate CAS 1392275-56-7

Product Description:

Product Name: Tenofovir Alafenamide Hemifumarate CAS NO: 1392275-56-7      

Synonyms:

1-MethylethylN-((S)-(((1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy)methyl)phenoxyphosphinoyl)-L-alaninate,(2E)-2-butenedioate;

Tenofovir alafenamide fumarate, 2:1;

L-Alanine,N-((S)-(((1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy)methyl)phenoxyphosphinyl)-,1-methylethyl ester,(2E)-2-butenedioate (2:1);

Chemical & Physical Properties:

Appearance: White to off-white solid powder     

Assay :≥99.0%

Storage: Store at Room Tem.

Safety Information:

Signal Word: Warning

Hazard Statements: H315; H319; H335

Precautionary Statements:

P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

A fumarate salt prepared from tenofovir alafenamide by reaction of one molecule of fumaric acid for every two molecules of tenofovir alafenamide. A prodrug for tenofovir, it is used in combination therapy for the treatment of HIV-1 infection.

Tenofovir fumarate alafenamide (TAF), an oral nucleoside transcriptase inhibitor developed by Gilead, is another prodrug of tenofovir fumarate dioproxil (TDF), being developed for hepatitis B virus infection (HBV) and acquired immune syndrome (HIV). Tenofovir alafenolamine fumarate can be used as a solvent, alkylation esterification and polymerization catalyst. 99% of the products are used in the pharmaceutical sector and 70% are used in the electroplating industry Chemicalbook. Nutritional drugs, combined with a low protein diet, are the core drugs for the prevention and treatment of damage caused by the disorder of protein metabolism due to chronic renal insufficiency and wasting dystrophy.

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